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Transport Phenomena In Biological Systems 2nd Edition.pdf fulnel




2017, 5:3 15 doi: 10.1186/s13104-017-2562-7 S.N.B. Truskey, Fan Yuan, David F. Katz Transport Phenomena in Biological Systems (2nd Edition) George A. Truskey, Fan Yuan, David F. Katz No portion of this article can be reproduced, stored in a retrieval system, or transmitted in any form without the written permission of the publisher, The Society for Experimental Biology and Medicine, Inc. This article may be freely read and used for non-commercial purposes. However, it may not be cited, reproduced, or redistributed in any form without written permission from the publisher. The editors regret that this reprint is the property of the Society for Experimental Biology and Medicine and is not available for a fee. 1. Introduction The aim of this article is to provide an up-to-date and authoritative reference on topics in transport phenomena in biology. The article is organized as follows: Section 2 covers non-membranous intracellular transport, including the transport of substances across the membranes of organelles and transport along cytoskeletal filaments and membrane-bound vesicles. Intracellular transport is important in fundamental cell biology as well as in many pathological processes. In addition, the question of whether transport inside cells can occur via macroscopic physical processes will be briefly discussed. Section 3 covers motility and transport in the extracellular space. Topics include cell motility, cytoskeletal organization and propulsion, and chemotaxis, as well as tissue structure and function. Section 4 covers nucleocytoplasmic transport and mechanisms of translational control. The traditional perspective of nuclear transport is that it consists of a series of steps in which the various components involved are delivered into the nucleus via the nuclear pores, the nuclear envelope. Recent work has shown that there are multiple routes, and that there are perhaps even more modes than was previously thought. For instance, nuclear import of proteins is now known to occur by a process in which proteins are taken up by the nucleus as whole molecules, rather than being transported into the nucleus as individual subunits. Nuclear transport of small molecules is also understood to occur by multiple routes. Another major line of research concerns the effects of various stresses on the structure and function of the nuclear envelope. This is important because all aspects of nuclear function, including transcription, DNA repair, and DNA replication, are intimately dependent on the architecture of the nucleus. The details of these processes and mechanisms



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Transport Phenomena In Biological Systems 2nd Edition.pdf fulnel

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